Anti-Granzyme-B [Fv17]
Product Sizes
1 mg
AB05101-10-3-BT-1MG
About this Product
- SKU:
- AB05101-10-3-BT
- Additional Names:
- GZMB; C11; CTLA-1; CTLA1; CTSGL1; CGL1; CSPB; GRB; HLP; SECT; Granzyme-2; Cathepsin G-like 1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Human lymphocyte protein; T-cell serine protease 1-3E
- Application:
- ELISA, Flow Cytometry, Immunoprecipitation
- Buffer:
- PBS
- translate.label.attr.clone:
- Fv17
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human scfv format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was isolated from a semi-synthetic phage library by panning against biotinylated human granzyme B.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds granzyme B, an abundant serine protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It has has been demonstrated to be a pivotal molecule for protective immunity against viral infection and cellular malignant transformation.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab05101-10.3-BT
