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Antibodies

Anti-uPAR [3C6]

Product Sizes
100 ug
Was £510.00 £484.00
AB05100-3-3-100UG
About this Product
SKU:
AB05100-3-3
Additional Names:
CD87; U-PAR; MO3; PLAUR; Urokinase plasminogen activator surface receptor; Monocyte activation antigen Mo3
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
3C6
Clonality:
Recombinant Monoclonal
Extra Details:
This is a reformatted mouse IgG2b Fc Silentâ„¢ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
The original antibody was isolated from a fully human naive Fab phage display library constructed from the conversion of peripheral blood lymphocyte RNA into cDNA. The particular antibody clone was isolated by panning the library against human soluble uPAR that was immobilized to a Nunc Maxisorp™.
Isotype:
IgG2b
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human urokinase plasminogen activator receptor (uPAR). It does not cross react with mouse or cynomolgus monkey uPAR. Human uPAR plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. Upregulation of uPAR expression at the cell surface, and plasminogen activation, has been linked to a numbe
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies