Anti-uPAR [3C6]
Product Sizes
100 ug
AB05100-3-0-100UG
About this Product
- SKU:
- AB05100-3-0
- Additional Names:
- CD87; U-PAR; MO3; PLAUR; Urokinase plasminogen activator surface receptor; Monocyte activation antigen Mo3
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 3C6
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The original antibody was isolated from a fully human naive Fab phage display library constructed from the conversion of peripheral blood lymphocyte RNA into cDNA. The particular antibody clone was isolated by panning the library against human soluble uPAR that was immobilized to a Nunc Maxisorp™.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human urokinase plasminogen activator receptor (uPAR). It does not cross react with mouse or cynomolgus monkey uPAR. Human uPAR plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. Upregulation of uPAR expression at the cell surface, and plasminogen activation, has been linked to a numbe
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab05100-3.0
