Anti-uPAR [2.6.1]
Product Sizes
1 mg
AB05099-10-3-BT-1MG
About this Product
- SKU:
- AB05099-10-3-BT
- Additional Names:
- CD87; U-PAR; MO3; PLAUR; Urokinase plasminogen activator surface receptor; Monocyte activation antigen Mo3
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 2.6.1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG2 format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing XenoMouse® with human uPAR expressed on the surface of B cells. Recovered lymphocytes from hyperimmunized mice are fused with a myeloid-type cell line to prepare immortal hybridoma cell lines. Antibodies from the cell supernatants are then screened by ELISA for reactivity against the uPAR immunogen.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human urokinase plasminogen activator receptor (uPAR). It also cross reacts with cynomolgus monkey UPAR. It plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. Upregulation of uPAR expression at the cell surface, and plasminogen activation, has been linked to a number of conditions incl
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab05099-10.3-BT
