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Antibodies

Anti-uPAR [8D3]

Product Sizes
100 ug
Was £510.00 £484.00
AB05098-10-3-100UG
About this Product
SKU:
AB05098-10-3
Additional Names:
CD87; U-PAR; MO3; PLAUR; Urokinase plasminogen activator surface receptor; Monocyte activation antigen Mo3
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
8D3
Clonality:
Recombinant Monoclonal
Extra Details:
This is a reformatted human IgG1 Fc Silent Fc Silentâ„¢ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by immunizing BALB/c mice with a combination of three synthetic peptides (AVTYSRSRYLEC, YSRSRYLEC, SRYLEC) derived from the linker region between D1 and D2 of uPAR, conjugated to Keyhole limpet hemocyanin (KLH).
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human urokinase plasminogen activator receptor (uPAR). It plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. Upregulation of uPAR expression at the cell surface, and plasminogen activation, has been linked to a number of conditions including inflammation, wound repair, arthritis, ather
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies