Anti-uPAR [8D3]
Product Sizes
1 mg
AB05098-10-0-BT-1MG
About this Product
- SKU:
- AB05098-10-0-BT
- Additional Names:
- CD87; U-PAR; MO3; PLAUR; Urokinase plasminogen activator surface receptor; Monocyte activation antigen Mo3
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 8D3
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with a combination of three synthetic peptides (AVTYSRSRYLEC, YSRSRYLEC, SRYLEC) derived from the linker region between D1 and D2 of uPAR, conjugated to Keyhole limpet hemocyanin (KLH).
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human urokinase plasminogen activator receptor (uPAR). It plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. Upregulation of uPAR expression at the cell surface, and plasminogen activation, has been linked to a number of conditions including inflammation, wound repair, arthritis, ather
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab05098-10.0-BT
