Anti-Aquaporin 4 [rAb58]
Product Sizes
1 mg
AB05081-10-3-BT-1MG
About this Product
- SKU:
- AB05081-10-3-BT
- Additional Names:
- AQP4; AQP-4; Aquaporin-4; MIWC; WCH4; Mercurial-insensitive water channel
- Application:
- Cell-based/Functional Assay, Flow Cytometry, Immunofluorescence
- Buffer:
- PBS
- translate.label.attr.clone:
- rAb58
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated from the PCR products obtained from the human B cell clones isolated from CSF plasma of an neuromyelitis optica (NMO-IgG) seropositive patient using a dual vector transient transfection system.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds an extracellular conformation specific epitope on the human aquaporin 4 (AQP4). It is capable of binding both M1 and M23 isoforms of AQP4. Aquaporin 4 is a water channel expressed on astrocytes throughout the CNS and in skeletal muscle and some epithelial cells outside of the CNS. It plays an important role in brain water homeostasis and in glymphatic solute transport. Neuromye
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab05081-10.3-BT
