Anti-Tryptase [E104.v2]
Product Sizes
100 ug
AB05037-3-3-100UG
About this Product
- SKU:
- AB05037-3-3
- Additional Names:
- TPSAB1; TPS1; TPS2; TPSB1; Tryptase-1; Tryptase alpha/beta-1; Tryptase I; Tryptase alpha-1; Beta tryptase; B Beta-type tryptase; B Beta tryptase; huE104.v2
- Application:
- ELISA
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- E104.v2
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The original antibody was generated by immunizing two rabbits with CHO-derived human tryptase beta 1 (tetramer) with Freund's complete adjuvant. The humanized version huE104.v2 was generated by grafting the CDRs of the rabbit antibody onto human framework regions.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human and cynomolgus monkey tryptase, which is a major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Elevated tryptase levels are found in subgroups of patients with mastocytosis, myelodysplastic syndrome, myeloproliferative neoplasm, acute myeloid leukemia, chronic myeloid leukemia (CML) and chronic
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab05037-3.3
