Anti-Tryptase [huR20H8]
Product Sizes
1 mg
AB05020-3-0-BT-1MG
About this Product
- SKU:
- AB05020-3-0-BT
- Additional Names:
- TPSAB1; TPS1; TPS2; TPSB1; Tryptase-1; Tryptase alpha/beta-1; Tryptase I; Tryptase alpha-1; Beta tryptase; B Beta-type tryptase; B Beta tryptase; R40B4VH+R64H6VK
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay
- Buffer:
- PBS
- translate.label.attr.clone:
- huR20H8
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The mouse antibody R20H8 was generated by immunizing BALB/c mice with recombinant hTPSB1 protein with a his tag and an enterokinase cleavage site. The humanized version R40B4 was created by using the classic framework transplantation strategy.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human and cynomolgus monkey tryptase, which is a major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Elevated tryptase levels are found in subgroups of patients with mastocytosis, myelodysplastic syndrome, myeloproliferative neoplasm, acute myeloid leukemia, chronic myeloid leukemia (CML) and chronic
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab05020-3.0-BT
