Anti-CTLA-4 [10D1 (Ipilimumab)]

Product Sizes

1 mg

AB04910-10-3-BT-1MG

About this Product

SKU:: AB04910-10-3-BT
Additional Names:: CTLA4; CD152; MDX-010; MDX-CTLA-4; MDX-CTLA4; YERVOY; BCD-145; nurulimab; BMS-734016; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4
Application:: Block/Inhibit/Neutralise, Cell-based/Functional Assay, Crystallography, ELISA, FACS, Flow Cytometry, Surface Plasmon Resonance, Western Blot
Buffer:: PBS
translate.label.attr.clone:: 10D1 (Ipilimumab)
Clonality:: Recombinant Monoclonal
Extra Details:: This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human format, created for improved compatibility with existing reagents, assays and techniques.
Formulation:: PBS only.
Host:: Human
Immunogen:: The original antibody was generated by immunizing transgenic mice with human CTLA-4.
Isotype:: IgG1
Purification:: Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Specificity:: This antibody binds CTLA-4. The antibody contacts the front B Beta-sheet of CTLA-4 and intersects with the CTLA-4:B Beta7 ligand recognition surface. The antibody cross reacts with macaque CTLA-4. The antibody does not recognise CD28.
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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