Anti-TNF alpha [CNTO-148 (Golimumab)]
Product Sizes
1 mg
AB04907-10-3-BT-1MG
About this Product
- SKU:
- AB04907-10-3-BT
- Additional Names:
- TNF-A Alpha; TNFA Alpha; TNF; TNFA; TNFSF; Tumor necrosis factor; Cachectin; TNFalpha; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; TNFa; CNTO148; CNTO 148; SIMPONI
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, Crystallography, Surface Plasmon Resonance
- Buffer:
- PBS
- translate.label.attr.clone:
- CNTO-148 (Golimumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original format of the antibody was generated by immunizing transgenic mice engineered to express human IgGs with human TNFa.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human TNF-alpha. The antibody binds a discontinuous epitope composed of residues in the AA' loop (Gly24), C strand (Lys65, Gln67T), CD loop (Ser71), EF loop (Glu104, Thr105, Pro106, Glu107, Gly108, Ala111), and GH loop (Arg138, Asp140, Tyr141) of TNF-alpha.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04907-10.3-BT
