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Antibodies

Anti-TNF alpha [hTNF40 (Certolizumab)]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB04906-23-0-BT-1MG
About this Product
SKU:
AB04906-23-0-BT
Additional Names:
TNF-A Alpha; TNFA Alpha; TNF; TNFA; TNFSF; Tumor necrosis factor; Cachectin; TNFalpha; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; TNFa; CDP870; PHA-738144; CIMZIA
Application:
Cell-based/Functional Assay, Crystallography
Buffer:
PBS
translate.label.attr.clone:
hTNF40 (Certolizumab)
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Rabbit
Immunogen:
The original antibody is a monovalent Fab fragment of a humanized anti-TNFA Alpha antibody and lacks the Fc region. Further, the hinge region is attached to two cross-linked chains of a 20-kDa polyethylene glycol (PEG).
Isotype:
IgG
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human TNF-alpha. In particular, the epitope is mostly located in the DE loop and GH loop regions of TNFA Alpha. Further, several residues on the epitope of are also involved in the TNFA Alpha-TNFR interaction.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies