Anti-CD28 [TGN1412 (Theralizumab)]
Product Sizes
1 mg
AB04902-10-0-BT-1MG
About this Product
- SKU:
- AB04902-10-0-BT
- Additional Names:
- T-cell-specific surface glycoprotein CD28; TP44; TGN1112; 5.11A1; CD28-SuperMAB; TAB08; 9D7
- Buffer:
- PBS
- translate.label.attr.clone:
- TGN1412 (Theralizumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original mouse antibody 5.11A1 was generated by immunizing BALB/c mice with recombinant human CD28-Fc fusion protein and boosted with B lymphoma cell line transfected with human CD28. Later on the CDRs of the original mouse antibody were cloned into human IgG1 framework regions to obtain the humanized antibody.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody is specific for human CD28. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04902-10.0-BT
