Anti-human insulin receptor [HIRMAb]
Product Sizes
1 mg
AB04886-10-3-BT-1MG
About this Product
- SKU:
- AB04886-10-3-BT
- Additional Names:
- CD220; HHF5; IR; HIR; INSR; HINSR; human insulin receptor monoclonal antibody; 83-14
- Application:
- Cell-based/Functional Assay, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- HIRMAb
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- This humanized antibody, based on the anti-insulin receptor alpha antibody clone 83-14 (Ab00137), was generated by grafting the complementarity-determining regions (CDRs) of the original murine IgG1 antibody onto the human B43 IgG1 heavy chain and the human REI kappa light chain frameworks.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for the endogenous human insulin receptor and binds an exofacial epitope within the 469-592 amino acid region of the receptor. This antibody cross-reacts with Rhesus monkey and mouse insulin receptors but does not cross the blood-brain barrier (BBB) in mice.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04886-10.3-BT
