Anti-ST2L [STLM208 (ST2H257)]
Product Sizes
1 mg
AB04870-10-3-BT-1MG
About this Product
- SKU:
- AB04870-10-3-BT
- Additional Names:
- ST2; IL1RL1; IL-1RL1; DER4; T1; IL-33RA Alpha; Interleukin-1 receptor-like 1; Protein ST2; Growth Stimulation Expressed Gene 2; suppression of tumorigenicity 2; ST2F6; ST2F14
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- STLM208 (ST2H257)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was isolated from a human Fab phage display library by panning against chimeric HHM-ST2L construct with the biotinylated antigen captured on streptavidin-coated magnetic beads. Phage selections were performed for three rounds followed by screening by ELISA for Fab binding to hST2L-Fc protein. The selected Fab was affinity matured and converted to a human IgG1 format.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody specifically binds an epitope in domain I of the human ST2L and cross reacts with cynomolgus monkey ST2L. ST2L a transmembrane receptor that belongs to the IL-1 receptor family which is expressed on the cell surface of a wide variety of immune cells including T cell, NK/NKT cells, basophils, eosinophils, mast cells and the newly-described non-B/non-T innate lymphoid type 2 cells, nuo
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04870-10.3-BT
