Anti-H3K27me3 [2E12LI]
Product Sizes
1 mg
AB04736-10-0-BT-1MG
About this Product
- SKU:
- AB04736-10-0-BT
- Additional Names:
- Trimethylated Histone H3 Lys27; trimethyl-Histone H3 (Lys27); histone H3; H3K27; Trimethylated histone H3; Histone H3 trimethylated at Lysine 27; nucleosome; H3K27ME3; post translational modification; histone post-translational modification; 2E12 mutant M86L/M158I; 2E12
- Application:
- Cell-based/Functional Assay, Immunofluorescence
- Buffer:
- PBS
- translate.label.attr.clone:
- 2E12LI
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with a 20-mer peptide (KQLATKAAR (trimethyl K) SAPATGGVKC) containing histone H3K27 trimethylated lysine and conjugated with KLH.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is capable of recognizing histone H3 proteins with a trimethylation at Lys27. It specifically recognizes and binds trimethyl lysine and amino acids surrounding it comprising KQLATKAAR(trimethyl K)SAPATGGVKC. Methylation is a type of post-translational modification (PTM) which is caused by covalent addition of methyl group to proteins, DNA or other molecules. PTMs have fundamental rol
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04736-10.0-BT
