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Antibodies

Anti-TLR4 [NI-0101]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB04582-10-0-BT-1MG
About this Product
SKU:
AB04582-10-0-BT
Additional Names:
hToll; CD284; Toll-like receptor 4; hu 15C1; hu15C1
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, Crystallization, ELISA, FACS, Flow Cytometry, Surface Plasmon Resonance
Buffer:
PBS
translate.label.attr.clone:
NI-0101
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was generated through a humanization process involving CDR grafting of the original mouse anti-TLR4 clone 15C1 onto selected human germline sequences and performing framework optimization.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for human TLR4 and binds the LRR 9 domain (residues 328-YN-329, 349-KLK-351); it engages both FcG GammaRI and FcG GammaRIIA, but not FcG GammaRIII.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies