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Antibodies

Anti-MUC-1 [VU-4H5 ]

Product Sizes
100 ug
Was £510.00 £484.00
AB04350-10-0-100UG
About this Product
SKU:
AB04350-10-0
Additional Names:
Mucin-1; CD227; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; VU4H5
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
VU-4H5
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by immunizing mice with a synthetic glycosylated MUC1 60mer tandem repeat NH2-(HGVTSAPDT(GalNAc)RPAPGSTAPPAHG)3-COOH, conjugated to bovine serum albumin.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody specifically binds to the core protein epitopes within the VNTR domain of human Muc-1 (PMID: 9422085). MUC-1 is a tumor associated antigen expressed on many multiple myelomas, breast and ovarian cancer cells. This antibody does not show reactivity towards fibroblasts, lymphoblastoid cells, and a large number of epithelial cell lines of non-breast origin.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies