Anti-CD49B [GBR500 (Vatelizumab, TMC-2206)]
Product Sizes
1 mg
£2163.00
AB04186-2-3-BT-1MG
About this Product
- SKU:
- AB04186-2-3-BT
- Additional Names:
- ITGA2; Integrin A Alpha2B Beta1; Integrin alpha-2/beta-1; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; BHA2.1; SAR339658
- Application:
- Block/Inhibit/Neutralise, ELISA, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- GBR500 (Vatelizumab, TMC-2206)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The parental mouse antibody was generated by immunizing BALB/c mice with human fibrosarcoma HT1080 cells. The original humanized version was generated by grafting the CDRs of murine parental antibody onto human acceptor framework regions.
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds an epitope in the domain I region of human A Alpha2 integrin. This epitope spans a region encompassing amino acid residues, K40, N73, Q89, Y93, R165, and N166 and optionally, other amino acid residues of the A Alpha2 integrin I domain. This antibody is also reported to cross react with cynomolgus monkey, rhesus macaque and rat A Alpha2 I domains. Integrin alpha-2/beta-1 is a re
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04186-2.3-BT
