Anti-Amyloid beta A4 protein [LY2062430 (Solanezumab, hu266)]
Product Sizes
1 mg
AB04185-3-3-BT-1MG
About this Product
- SKU:
- AB04185-3-3-BT
- Additional Names:
- APP; AB Beta peptide; Abeta; A-beta; AB Beta; AB Beta42; amyloid beta peptide; Alzheimer disease amyloid protein; Beta-amyloid precursor protein; Protease nexin-II; humanized m266.2
- Application:
- ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- LY2062430 (Solanezumab, hu266)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The parental mouse antibody 266 was generated by immunization of mice with a peptide composed of residues 13-28 of human AB Beta peptide. The original humanized version of the antibody was generated by grafting CDRs of the mouse antibody onto human framework regions.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognizes amino acids 13-28 of amyloid beta and only recognized soluble form of the amyloid beta peptide. It functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04185-3.3-BT
