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Antibodies

Anti-FAP alpha [BIBH1 (Sibrotuzumab, huF19)]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB04184-10-0-BT-1MG
About this Product
SKU:
AB04184-10-0-BT
Additional Names:
Seprase; Fibroblast activation protein; Prolyl endopeptidase FAP; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Fibroblast activation protein alpha; Gelatin degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease
Application:
ELISA, Flow Cytometry, Immunohistochemistry
Buffer:
PBS
translate.label.attr.clone:
BIBH1 (Sibrotuzumab, huF19)
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Human
Immunogen:
The parental mouse antibody F19 was generated by immunizing mice with lung fibroblasts. The original humanized version of the antibody was generated by grafting of CDRs from the parental mouse antibody onto human framework regions.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds specifically to human fibroblast activation protein (FAP). This protein is a cell surface glycoprotein serine protease that participates in extracellular matrix degradation and is involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. This antibody does not cross react with rat, mouse, rabbit or cynomolgus monkey
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies