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Antibodies

Anti-IgG [RF61]

Product Sizes
100 ug
Was £510.00 £484.00
AB04107-1-1-100UG
About this Product
SKU:
AB04107-1-1
Additional Names:
IgG1; IgG2; IgG3; IgG4; Immunoglobulin G; Immunoglobulin gamma-1; Immunoglobulin G subclass 1; Immunoglobulin gamma-2; Immunoglobulin G subclass 2; Immunoglobulin gamma-3; Immunoglobulin G subclass 3; Immunoglobulin gamma-4; Immunoglobulin G subclass 4; 274.RA.F4; RF mAb 61; mAb 61
Application:
Agglutination, ELISA
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
RF61
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgM format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
The original antibody was produced by an Epstein Barr virus (EBV)-transformed B-cell line prepared from peripheral CD5+ blood lymphocytes of a Gm(a-), (x-), (b+), (g-), (f+) patient with classical rheumatoid arthritis (RA).
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for the C-terminal (CG Gamma3) end of the Fc region of IgG1, -2, and -3, with ~10-fold lower affinity for IgG4. This antibody's binding to IgG Fc is non-inhibitable by S. aureus protein A (SpA), which binds IgG Fc at the CG Gamma2-CG Gamma3 interface; this antibody's epitope is almost as far as physically possible from the antigen-combining site of IgG and is also remote
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Secondary Antibodies