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Antibodies

Anti-DR4 [HGS-ETR1 (Mapatumumab; TRM-1)]

Product Sizes
100 ug
Was £510.00 £484.00
AB04097-10-0-100UG
About this Product
SKU:
AB04097-10-0
Additional Names:
CD261; TR4; TNFRSF10A; APO2; TRAILR1; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; T1014A04
Application:
Activate/Stimulate, Cell-based/Functional Assay, ELISA
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
HGS-ETR1 (Mapatumumab; TRM-1)
Clonality:
Recombinant Monoclonal
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was isolated from a human scFv library by panning against human TR4 fusion protein. Later on the scFv version of this antibody was converted to human IgG1 version for carrying out further studies.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human CD261 (TR4 or TRAILR1 or TNFRSF10A). This protein acts as a receptor for the cytotoxic ligand TNFSF10/TRAIL and transduces cell death signal and induces cell apoptosis.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies