Anti-DM1 [06CT8.1.1.1]
Product Sizes
100 ug
AB04093-10-0-100UG
About this Product
- SKU:
- AB04093-10-0
- Additional Names:
- Mertansine; Maytansinoid
- Application:
- ELISA
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 06CT8.1.1.1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with DM1-cysteine-KLH conjugate.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Wide/Non-species Specific
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds maytansine (DM1), a thiol-containing maytansinoid which is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations. The potent cell killing ability of maytansine can be used in a targeted delivery approach, such as an antibody-drug conjugate (ADC), for the selective delivery of the drug and destruction of ca
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04093-10.0
