Anti-MMAE [AbAb-MMAE01]
Product Sizes
1 mg
AB04090-10-3-BT-1MG
About this Product
- SKU:
- AB04090-10-3-BT
- Additional Names:
- Monomethylauristatin E; Vedotin; USAN; monomethyl auristatin F; NMAF; auristatins
- Application:
- ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- AbAb-MMAE01
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with MMAE small molecule antigen in equal volume of complete Freund's adjuvant.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Wide/Non-species Specific
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds auristatin (MMAE, MMAF) which is a cytotoxic drug (payload) employed in the ADC field. Monomethyl auristatin E (MMAE, vedotin) is a very potent antimitotic agent that inhibits cell division by blocking the polymerization of tubulin. The family of auristatins are synthetic analogues of the antineoplastic natural product Dolastatin 10, ultrapotent cytotoxic microtubule inhibitors
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04090-10.3-BT
