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Antibodies

Anti-Factor VIII [EL-16]

Product Sizes
100 ug
AB04010-1-1-100UG
About this Product
SKU:
AB04010-1-1
Additional Names:
AHF; FVIII; Factor 8; anti-hemophilic factor; Coagulation factor VIII; procoagulant component; IT2
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
EL-16
Clonality:
Recombinant Monoclonal
Extra Details:
This full-length, chimeric mouse antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
The original antibody was isolated from a human phage display library generated from the peripheral blood of an inhibitor patient and panning the library against factor VIII light chain.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds the C2 domain of the human factor VIII, a glycoprotein involved in blood coagulation. Factor VIII acts as a cofactor for factor IXa which converts factor X to the activated form Xa in the presence of calcium and phospholipids. Defects in the F8 gene, which encodes Factor VIII, result in the coagulation disorder hemophilia A.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies