Anti-Factor VIII [KM41]
Product Sizes
500 ug
AB04009-30-11-BT-500UG
About this Product
- SKU:
- AB04009-30-11-BT
- Additional Names:
- AHF; FVIII; Factor 8; anti-hemophilic factor; Coagulation factor VIII; procoagulant component
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- KM41
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human scFv antibody, based on the original human scFv format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Immunogen:
- The original antibody was isolated from a human phage display library generated from the peripheral blood of an inhibitor patient and panning the library against factor VIII light chain.
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds and epitope between amino acid R1803-K1818 of the A3-C1 domains of the human factor VIII, which also contain binding site for factor IXa. Factor VIII is a glycoprotein involved in blood coagulation. Factor VIII acts as a cofactor for factor IXa which converts factor X to the activated form Xa in the presence of calcium and phospholipids. Defects in the F8 gene, which encodes Fa
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04009-30.11-BT
