Anti-Factor VIII [KM41]

Product Sizes

100 ug

AB04009-10-0-100UG

About this Product

SKU:: AB04009-10-0
Additional Names:: AHF; FVIII; Factor 8; anti-hemophilic factor; Coagulation factor VIII; procoagulant component
Application:: Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
Buffer:: PBS with 0.02% Proclin 300.
translate.label.attr.clone:: KM41
Clonality:: Recombinant Monoclonal
Extra Details:: This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Formulation:: PBS with 0.02% Proclin 300.
Host:: Human
Immunogen:: The original antibody was isolated from a human phage display library generated from the peripheral blood of an inhibitor patient and panning the library against factor VIII light chain.
Isotype:: IgG1
Purification:: Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Specificity:: This antibody binds and epitope between amino acid R1803-K1818 of the A3-C1 domains of the human factor VIII, which also contain binding site for factor IXa. Factor VIII is a glycoprotein involved in blood coagulation. Factor VIII acts as a cofactor for factor IXa which converts factor X to the activated form Xa in the presence of calcium and phospholipids. Defects in the F8 gene, which encodes Fa
Storage Conditions:: 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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