Anti-TROP2 [hRS7 (Sacituzumab)]
Product Sizes
1 mg
£2163.00
AB03992-3-3-BT-1MG
About this Product
- SKU:
- AB03992-3-3-BT
- Additional Names:
- EGP-1; TACSTD2; GA733-1; M1S1; TROP-2; Tumor-associated calcium signal transducer 2; epithelial glycoprotein-1 antigen; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1; IMMU-132; RS7; RS7-3G11
- Application:
- Cell-based/Functional Assay, Flow Cytometry, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- hRS7 (Sacituzumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The parental mouse antibody RS7-3G11 was generated by immunizing mice with crude membrane preparation of a human primary squamous cell carcinoma from the lung. The humanized version of this antibody called hRS7 was generated by grafting CDRs of the parental mouse antibody onto human framework regions.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human TROP2 (EGP-1) protein, which functions in a variety of cell signaling pathways and was first elucidated as a transducer of an intracellular calcium signal. Trop-2 is involved in several cell signaling pathways, of which many are associated with tumorigenesis. This antigen is found in many epithelial cancers, including carcinomas of the lung, bladder, breast, cervix, ovary
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03992-3.3-BT
