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Antibodies

Anti-CD47 [105D11]

Product Sizes
100 ug
AB03948-10-0-100UG
About this Product
SKU:
AB03948-10-0
Additional Names:
IAP; MER6; OV-3; Leukocyte surface antigen CD47; Antigenic surface determinant protein OA3; Integrin-associated protein; Protein MER6; ovarian cancer marker
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
105D11
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by immunizing BALB/c mice with recombinant human CD47-mFc fusion protein.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds the extracellular domain of the human CD47 and cross reacts with cynomolgus monkey CD47. CD47 is broadly distributed on normal adult tissues, as well as ovarian tumors, and is especially abundant in some epithelia and the brain. IAP or integrin associated protein has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies