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Antibodies

Anti-CD155 [scFv3]

Product Sizes
100 ug
AB03903-10-3-100UG
About this Product
SKU:
AB03903-10-3
Additional Names:
PVR; PVS; NECL-5; Poliovirus receptor; Nectin-like protein 5
Application:
Cell-based/Functional Assay
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
scFv3
Clonality:
Recombinant Monoclonal
Extra Details:
This full-length, chimeric human antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was isolated from an scFv phage display library generated by immunizing two BALB/c mice intradermally with paraformaldehyde fixed HT1080 cells (human fibrosarcoma cell line).
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human CD155 also called the poliovirus receptor (PVR). This protein mediates NK cell adhesion and triggers NK cell function. It also binds two NK cell receptors CD96 and CD226. CD155 is gaining more interest as a therapeutic target in the field of tumor immunology due to its prominent endogenous and immune functions.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies