Anti-Factor H binding protein [clone4]
Product Sizes
100 ug
AB03893-1-1-100UG
About this Product
- SKU:
- AB03893-1-1
- Additional Names:
- fHbp; GNA1870; Genome-derived Neisseria antigen 1870; Lipoprotein 2086
- Application:
- ELISA
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- clone4
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The recombinant fHbp protein of Neisseria meningitidis was used as the antigen for the immunization of BALB/c mice. Anti-fHbp VH/k chain ribosome display libraries was generated and the actual antibody was obtained by panning the scFv library against the recombinant fHbp protein by using a single round of the ribosome display method via a rabbit reticulocyte lysate system.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Bacteria
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds a surface exposed epitope on N. meningitidis FHbp, a virulence factor critical for surviving of the bacteria in the human host. FHbp protein is a bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH). Neisseria meningitidis is the leading global cause of meningitis and sepsis.
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03893-1.1
