Anti-Factor H binding protein [1A12 (9B)]
Product Sizes
1 mg
AB03892-23-0-BT-1MG
About this Product
- SKU:
- AB03892-23-0-BT
- Additional Names:
- fHbp; GNA1870; Genome-derived Neisseria antigen 1870; Lipoprotein 2086
- Application:
- Crystallography, ELISA, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 1A12 (9B)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rabbit
- Immunogen:
- The original antibody was generated from the peripheral blood plasmablast cells from three humans immunized with vaccines containing FHbp. The natively paired VH and VL genes were expressed in Escherichia coli to obtain recombinant antibody fragments (Fabs).
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Bacteria
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds a surface exposed epitope on N. meningitidis FHbp, a virulence factor critical for surviving of the bacteria in the human host. This antibody binds equally well to fHbp variants, including representative variants in variant groups 1, 2 or 3. FHbp protein is a bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH). Neisseria meningitidis is the
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03892-23.0-BT
