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Antibodies

Anti-DPGA anthrax [11D ]

Product Sizes
500 ug
Was £2625.00 £2494.00
AB03883-15-0-BT-500UG
About this Product
SKU:
AB03883-15-0-BT
Additional Names:
DPGA; capsular antigen; G GammaDPGA; gamma DPGA; poly-gamma-d-glutamic acid; poly-G Gamma-d-glutamic acid; antiphagocytic polypeptide capsule
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
Buffer:
PBS
translate.label.attr.clone:
11D
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Chimpanzee IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was generated by immunizing a chimpanzee with fragmented peptides of poly-G Gamma-D-glutamic acid (G GammaDPGA) capsule of B. anthracis conjugated with either B. anthracis recombinant protective antigen (rPA) or tetanus toxoid (TT).
Isotype:
IgM
Purification:
Purified
Reactivities:
Bacteria
Shipping Conditions:
Blue Ice
Specificity:
This antibody specifically binds the poly-G Gamma-D-glutamic acid (G GammaDPGA) capsule of Bacillus anthracis. Bacillus anthracis is surrounded by an antiphagocytic polypeptide capsule composed of poly G Gamma-d-glutamic acid (G GammaDPGA). The G GammaDPGA capsule shields the vegetative form of B. anthracis from agglutination by monoclonal antibodies to its cell wall polysaccharide. G GammaDPGA ha
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies