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Antibodies

Anti-KRAS G12D mutant [D113]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB03877-1-1-BT-1MG
About this Product
SKU:
AB03877-1-1-BT
Additional Names:
K-Ras; GTPase Kras; KRAS2; RASK2; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras; ras p21 protein; p21 ras; D113-2-1
Application:
ELISA
Buffer:
PBS
translate.label.attr.clone:
D113
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Mouse
Immunogen:
The original antibody was generated by immunizing mice with a synthetic dodecapeptide 'KLVVVGADGVGK'.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds the G12D mutant form of human KRAS protein. This ras protein binds GDP/GTP and possess intrinsic GTPase activity, that results in conversion of nucleotide guanosine triphosphate (GTP) into guanosine diphosphate (GDP). This protein plays an important role in many signal transduction pathways and regulation of cell proliferation. Somatic KRAS mutations are highly observed in leuk
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies