Anti-IDH1 mutant [MsMab-1]
Product Sizes
1 mg
AB03871-10-3-BT-1MG
About this Product
- SKU:
- AB03871-10-3-BT
- Additional Names:
- IDH; IDH1; IDPc; Isocitrate dehydrogenase [NADP] cytoplasmic; Isocitrate dehydrogenase 1; Cytosolic NADP-isocitrate dehydrogenase; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; IDH2; Isocitrate dehydrogenase [NADP]; mitochondrial; ICD-M; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- MsMab-1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing BDF1 mice with synthetic IDH1-R132G peptide of 19 amino acids (GGVKPIIIGGHAYGDQYRA) conjugated with KLH.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human isocitrate dehydrogenase 1 (IDH1) having R132H, R132C, R132S, R132G and R132L mutations and does not cross react with wild-type IDH1 protein. It also recognizes IDH2-R172M (GGTKPITIGMHAHGDQYKA) and IDH2-R172S (GGTKPITIGSHAHGDQYKA). IDH1 is an enzyme that catalyzes the NADP+-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglu
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03871-10.3-BT
