Anti-TIGIT [1F4]
Product Sizes
100 ug
AB03858-10-3-100UG
About this Product
- SKU:
- AB03858-10-3
- Additional Names:
- T-Cell-Ig and ITIM domain; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 1F4
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing hamsters with murine TIGIT-Fc fusion protein.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody is specific for human TIGIT. TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
- Storage Conditions:
- 2-8[o]C Aliquot.
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03858-10.3
