Anti-Claudin-18.2 [CLDN18.2-v.19]
Product Sizes
1 mg
AB03747-23-0-BT-1MG
About this Product
- SKU:
- AB03747-23-0-BT
- Additional Names:
- CLDN18.2; 2C6.9-HZ21; HuCLDN18.2-v. 19; CLDN18.2 v. 19
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- CLDN18.2-v.19
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rabbit
- Immunogen:
- The original antibody was generated by grafting CDRs of the parental mouse antibody onto human framework regions.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for human claudin-18.2 with no cross reactivity with claudin 18.1. Alterations in claudin expression can impair tight junction function, influence signaling pathways, and act as a tumor-promoting event in some epithelial cancers. Claudin 18.2 is overexpressed in various tumor type and is found to be a potentially important target in advanced gastric cancer.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03747-23.0-BT
