Anti-CD112 [Nec8-4116-8]
Product Sizes
1 mg
AB03746-10-3-BT-1MG
About this Product
- SKU:
- AB03746-10-3-BT
- Additional Names:
- Nectin-2; NECTIN2; HVEB; PRR2; PVRL2; Herpes virus entry mediator B; Herpesvirus entry mediator B; Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- Nec8-4116-8
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated be immunizing KM mice with an emulsion prepared by mixing the Nectin-2ED-Fc protein and Nectin-2ED-FLAG protein.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human CD112 (Nectin-2) and cross reacts with cynomolgus monkey CD112. It is also capable of binding AN77-78PD, G113R and H128R mutants of human CD112. Nectin-2 acts as a modulator of T-cell signaling. It can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine pr
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03746-10.3-BT
