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Antibodies

Anti-IL23 (p19) [G23-8]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB03741-2-0-BT-1MG
About this Product
SKU:
AB03741-2-0-BT
Additional Names:
IL23A; IL-23p19; IL23p19; IL23-p19; IL-23p19; SGRF; Interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19
Application:
Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
Buffer:
PBS
translate.label.attr.clone:
G23-8
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Mouse
Immunogen:
The original antibody was generated by immunizing rats with recombinant mouse IL-23 heterodimer.
Isotype:
IgG2a
Purification:
Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds p19 subunit of mouse interleukin-23 (IL-23). IL-23A associates with IL-12B to form IL-23 interleukin which is a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies