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Antibodies

Anti-HLA-E [3D12]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB03740-10-3-BT-1MG
About this Product
SKU:
AB03740-10-3-BT
Additional Names:
HLAE; sHLA-E; HLA-6.2; HLA class I histocompatibility antigen alpha chain E; Major histocompatibility complex class I E; MHC; MHC class I antigen E; MHC HLA E alpha 1; MHC HLA E alpha 2.1; HLAB; HLA-B; HLA-C; HLAC
Application:
Cell-based/Functional Assay, Flow Cytometry, Immunofluorescence
Buffer:
PBS
translate.label.attr.clone:
3D12
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was generated by immunizing HLA-B27 transgenic mice with recombinant human HLA-E purified from AEH cells (Lymphoblastoid cell line LCL 721.221 cells transfected with HLA-E gene).
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds an extracellular epitope on the human HLA-E, a member of human leukocyte antigen family. This antibody is capable of reacting with free HLA-E heavy chain as well as heavy chain associated with b2-microglobulin and peptide. This antibody is reported to cross react with HLA-B and HLA-C but not with HLA-A, HLA-F or HLA-G. The human HLA-E is a non-classical MHC class 1B molecule in
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies