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Antibodies

Anti-E2 [10B5 (RS10B5huFc)]

Product Sizes
100 ug
Was £510.00 £484.00
AB03729-23-0-100UG
About this Product
SKU:
AB03729-23-0
Additional Names:
WEEV E2; Envelope glycoprotein; E2 envelope glycoprotein; Structural polyprotein; Spike glycoprotein E2; p130; Alphavirus; 10B5 E7E2
Application:
ELISA
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
10B5 (RS10B5huFc)
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Rabbit
Immunogen:
The original antibody was generated by sequencing the total mRNA obtained from murine 10B5 E7E2 hybridoma. Recombinant 10B5 scFv-M13 phage were rescued from the clones and panned against WEE antigen immobilized on PVC 96-well plates. Later on mouse/human IgG1 chimeric version of the antibody was generated by using variable regions derived from the mouse 10B5 hybridoma and human Fc regions.
Isotype:
IgG
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds the E2 envelope polyprotein of the Western equine encephalitis virus (WEEV), which is a mosquito-borne arbovirus (arthropod-borne virus) and the causative agent of western equine encephalitis (WEE). WEEV belongs to the genus Alphavirus in the family Togaviridae. The virus is transmitted to people and horses by bites from infected mosquitoes (Culex tarsalis and Aedes taeniorhync
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies