Anti-Sclerostin [AbD09097]
Product Sizes
1 mg
AB03705-10-0-BT-1MG
About this Product
- SKU:
- AB03705-10-0-BT
- Additional Names:
- SOST
- Application:
- Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- AbD09097
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was isolated from the HuCAL GOLD library by panning against mouse sclerostin protein biotinylated using EZ-link Sulfo-NHS-LC-Biotin and coupled to streptavidin-coated magnetic beads.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds mouse sclerostin and cross reacts with human sclerostin and recognizes an epitope adjacent to sclerostin's binding site for the Wnt co-receptor LRP6. Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain which is produced in osteocytes (type of bone cell). The glycoprotein sclerostin has been identified as a negative regulator of bone growth t
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03705-10.0-BT
