Anti-IL-1B [IC8]
Product Sizes
100 ug
AB03654-10-3-100UG
About this Product
- SKU:
- AB03654-10-3
- Additional Names:
- IL1B; IL-1B Beta; 1L1F2; Interleukin-1 beta; IL-1 beta; Catabolin; 1C8
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- IC8
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original mouse antibody was generated by immunizing mice with human IL-1B protein. The humanized version was generated by grafting CDRs of the original mouse antibody onto human framework regions.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human Interleukin-1 beta, which is a potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. It promotes Th17 differentiation of T-cells and
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03654-10.3
