Anti-PAI-1 [MEDI-579]
Product Sizes
1 mg
AB03644-2-0-BT-1MG
About this Product
- SKU:
- AB03644-2-0-BT
- Additional Names:
- SERPINE1; PAI1; PAI; PLANH1; Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; Serpin E1; Humanized Ab167; MEDI579; Antibody 08
- Application:
- Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- MEDI-579
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This full-length, chimeric mouse antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The original antibody was isolated from a human scFv library by panning on recombinant human and rat PAI-1 followed by screening in a PAI-1/tPA competition binding assay.
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds the reactive center loop (RCL) of human PAI-1 and at the same exosite used by both tissue and urokinase plasminogen activators (tPA and uPA). This antibody binds the active form of human PAI-1. Plasminogen activator inhibitor-1 (PAI-1), is a serine protease inhibitor, a unique member of the serpin superfamily which plays an important role in fibrinolysis and is an established r
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03644-2.0-BT
