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Antibodies

Anti-Integrin alpha 5 beta 1 [SG/19]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB03564-10-0-BT-1MG
About this Product
SKU:
AB03564-10-0-BT
Additional Names:
CD29; ITGB1; FNRB; MDF2; MSK12; ITGA5:ITGB1; Integrin alpha V beta1; Integrin beta-1; Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; VLA-4 subunit beta
Application:
Cell-based/Functional Assay, Flow Cytometry, Immunofluorescence, Immunoprecipitation
Buffer:
PBS
translate.label.attr.clone:
SG/19
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was generated by immunizing BALB/c mice with Nalm-6 cells.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human integrin alpha 5 beta 1 near the N-terminus. Epitope mapping of SG/19 revealed that Thr82 in the 1 subunit, located at the outer face of the boundary between the I-like and hybrid domains, was the key binding determinant for this antibody. Integrin alpha5 beta 1 is also known as fibronectin receptor and binds matrix macromolecules and proteinases and thereby stimulates an
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies