Anti-pre-fusion viral F protein [MPE8]

Product Sizes

1 mg

AB03555-10-0-BT-1MG

About this Product

SKU:: AB03555-10-0-BT
Additional Names:: Human respiratory syncytial virus; HRSV; human metapneumovirus; HMPV; Fusion glycoprotein F0; Protein F; PVM; BRSV
Application:: Block/Inhibit/Neutralise, Cell-based/Functional Assay, Crystallization, ELISA, Surface Plasmon Resonance, Western Blot
Buffer:: PBS
translate.label.attr.clone:: MPE8
Clonality:: Recombinant Monoclonal
Formulation:: PBS only.
Host:: Human
Immunogen:: The original antibody was generated by isolating IgG1 memory B cells of a blood donor with high serum neutralizing antibody titres against HRSV and HMPV.
Isotype:: IgG1
Purification:: Purified
Reactivities:: Virus
Shipping Conditions:: Blue Ice
Specificity:: The antibody binds to HRSV, HMPV, bovine RSV (BRSV) and pneumonia virus of mice (PVM). The antibody binds to a highly conserved epitope that is displayed on the surface of the pre-fusion, but not of the post-fusion, HRSV and HMPV F proteins. The epitope is centred around the b2/b7 antiparallel strands and relies on residues T50, D305, G307, I309 and D310, which are highly conserved amongst 551 vir
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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