Anti-F protein [2E3]
Product Sizes
100 ug
AB03523-23-0-100UG
About this Product
- SKU:
- AB03523-23-0
- Additional Names:
- fusion glycoprotein; Fusion glycoprotein F0
- Application:
- Block/Inhibit/Neutralise, ELISA, Surface Plasmon Resonance
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 2E3
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Rabbit
- Immunogen:
- A synthetic, fully human antibody library was used for panning against RSV prefusion and post fusion F proteins. The original antibody against RSV F protein was discovered following phage library panning and characterized.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- The original antibody is specific for prefusion F protein. The antibody binds the protein through a conformational epitope spanning across three distinct sections of the RSV F protein: residues 419-434, 443-448, and 459-467. F-protein plays a pivotal role in the pathogenesis of RSV by mediating the fusion between the viral and the host cell membrane. F protein exists in two distinct conformations:
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03523-23.0
