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Antibodies

Anti-Kinetochore protein NDC80 homolog [Hec1 (9G3)]

Product Sizes
100 ug
Was £510.00 £484.00
AB03500-23-0-100UG
About this Product
SKU:
AB03500-23-0
Additional Names:
NDC80; HEC; HEC1; KNTC2; Highly expressed in cancer protein; Kinetochore protein Hec1; HsHec1; Kinetochore-associated protein 2; Retinoblastoma-associated protein HEC
Application:
Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
Hec1 (9G3)
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Rabbit
Immunogen:
The original antibody was generated in mice by immunization with a purified protein fragment encompassing amino acids 56-632 of the human Hec1 protein.
Isotype:
IgG
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody specifically binds amino acids 200-215 in the N terminal globular domain of the human Hec1 protein, exterior to Spc24 at metaphase kinetochores. It binds in a region which resides within the well-ordered calponin homology domain of the protein. Hec 1 protein acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spi
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies