Anti-Kinetochore protein NDC80 homolog [Hec1 (9G3)]
Product Sizes
1 mg
AB03500-10-0-BT-1MG
About this Product
- SKU:
- AB03500-10-0-BT
- Additional Names:
- NDC80; HEC; HEC1; KNTC2; Highly expressed in cancer protein; Kinetochore protein Hec1; HsHec1; Kinetochore-associated protein 2; Retinoblastoma-associated protein HEC
- Application:
- Immunofluorescence, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- Hec1 (9G3)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated in mice by immunization with a purified protein fragment encompassing amino acids 56-632 of the human Hec1 protein.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody specifically binds amino acids 200-215 in the N terminal globular domain of the human Hec1 protein, exterior to Spc24 at metaphase kinetochores. It binds in a region which resides within the well-ordered calponin homology domain of the protein. Hec 1 protein acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spi
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03500-10.0-BT
